HCV full-length genome reconstruction with sequence independent amplification combined with next generation sequencing
نویسندگان
چکیده
منابع مشابه
A18 Random amplification with next-generation sequencing to cover HIV and HCV full-length genomes
Stop codon mutation on Pre-Core, G1896A, was found in 23 of 98 patients (23.47%); among them, 20 of 23 (86.96%) are genotype B. Mutations related to antiviral drug resistance with frequency more than 1% in the reverse transcriptase (RT) domain of Polymerase gene were identified. 83.67% sequences have more than one mutation. 50% sequences have mutation at rtI169V/M, and all belong to sub-genotyp...
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ژورنال
عنوان ژورنال: Retrovirology
سال: 2012
ISSN: 1742-4690
DOI: 10.1186/1742-4690-9-s1-o6